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What are the side effects of high Prograf levels? Common side effects may include: fever, infections, anemia; high blood sugar, high potassium levels, low magnesium or phosphate levels; tremors; nausea, diarrhea, constipation, stomach pain; numbness or tingling; headache, general pain; sleep problems (insomnia); or. swelling in your hands or feet.
What causes tacrolimus levels to rise? It is well known that during diarrhea episodes decreased cyclosporine and tacrolimus levels are often observed, usually requiring an increase in dose. An increase in tacrolimus trough levels is infrequently recognized as a potential cause of the adverse effect of severe diarrhea.
What are the risks of taking immunosuppressants? The most significant side effect of immunosuppressant drugs is an increased risk of infection. Other, less serious side effects can include loss of appetite, nausea, vomiting, increased hair growth, and hand trembling. These effects typically subside as the body adjusts to the immunosuppressant drugs.
What is responsible for transplant rejection? Transplant rejection occurs when transplanted tissue is rejected by the recipient's immune system, which destroys the transplanted tissue.
How is acute kidney rejection treated? Treatment starting with intravenous solumedrol 250–500 mg daily for 3 days is a common practice. Treatment of acute cellular rejection with an anti–T-cell antibody (muromonab [OKT3], ATG or ALG) is more ef- fective in restoring kidney function and preventing graft loss than treatment with corticosteroids (105).
How long does a transplanted liver last? A transplanted liver will function for five years or more in 70 percent of recipients, and even longer if the organ came from a living donor. After a heart transplant, the five-year survival rate for the organ is about 76 percent.
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